The physician who performed the test can provide resources to help with avoidance measures. Butylene glycol may help condition your hair and make your skin feel softer. El-Sayed F, Bayle-Lebey P, Marguery MC, Bazex J. Stacy Wiegman, PharmD. Potential life-threatening hypersensitivity reactions to hidden molecules like macrogol may be underdiagnosed. It looks like you have javascript turned off. This site needs JavaScript to work properly. NIH Free of allergy causing parabens and related esters such as benzocaine, PPD and others. However, highly processed ingredients derived from wheat, barley, rye, and oat (e.g., glycerin or tocopherol) will not be excluded by SkinSAFE. LipSafe is the same as "Top Free" and free of LANOLIN too,  Lip Safe aka the kissing badge keeps your lips more kissable. Propylene glycol causes allergic reactions in some patients. 2014 Jan;32(1):1-11. doi: 10.1016/j.det.2013.09.006. Immediate and … I can't any of the 'ols - alcohol, zylotol, mannitol - all the sugar alcohols. University of Illinois Urbana-Champaign North Shore Center for Medical Aesthetics Northbrook, IL. Although this type of response to PEG 3350 is rare, it is helpful to know which symptoms you should look for and when you should call your doctor. Allergic contact dermatitis to pentylene glycol in a cosmetic cream Contact Dermatitis. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. the allergist I see doesn’t think its due to those allergies but possibly an intolerance to suites!! An_259851 posted: I was diagnosed with a PG allergy last April after suffering with dermatitis for 10 mos. Propylene glycol is a synthetic food additive that belongs to the same chemical group as alcohol. Allergic contact dermatitis to ethylhexylglycerin and pentylene glycol Allergic contact dermatitis to ethylhexylglycerin and pentylene glycol Mortz, Charlotte Gotthard; Otkjær, Aksel; Andersen, Klaus Ejner 2009-09-01 00:00:00 Preservative allergy is one of the main reasons for allergic contact dermatitis caused by cosmetic products. 2009 Sep;61(3):180. doi: 10.1111/j.1600-0536.2009.01586.x. Patch testing to the cream and its ingredients revealed positive reactions to both propyl gallate and pentylene glycol. 2003 Mar;48(3):176-7. doi: 10.1034/j.1600-0536.2003.00073.x. Skin testing has been described by Wylon et al (1). Free of added nickel and cobalt related ingredients. Contact Dermatitis. Free of formaldehyde and the most common allergy causing preservatives such as benzalkonium chloride, formaldehyde, benzophenone, methyldibromo glutaronitrile, MCI/MI and others. Free of harmful hormone-altering chemicals and ingredients that may affect teen development, such as Phthalates, Parabens, Triclosan, Benzophenone-3 and related ingredients. Free of the top common allergy causing ingredients (fragrances, preservatives, topical antibiotics, sunscreens and metals), surfactants (cocamidopropyl betaine) and harmful hormone-altering chemicals and ingredients. For those sensitive to PG, the most common consequence is excessive irritation and a sore, dry throat when inhaling PG-based liquids, but in some cases more typical allergic reactions can occur. Complete remission followed avoidance of the offending substances. ! I basically know how to get PG out of my life through food ,medicines and cleaning supplies, but I'm having trouble with it "out in the world". SkinSAFE may earn a portion of sales from products that are purchased through our site as part of our affiliate partnership with retailers. If you're allergic to any glycol, you're allergic to them all. HHS Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body. Well, welcome to that help! Irritant free beauty, skincare & household products. Pentylene glycol does not have any evidence to suggest toxicity or carcinogenicity. . Our Soy filter excludes products with soy ingredients (e.g., soybean oil). COVID-19 is an emerging, rapidly evolving situation. Vieira V, Calhelha RC, Barros L, Coutinho JAP, Ferreira ICFR, Ferreira O. Molecules. because it is in processed foods. Propylene glycol may produce eczematous skin reactions of toxic and, more rarely, of allergic nature. Pharmacy. Cosmesis Skin Care Skin Stem Cell Serum, 1 fl oz. It was not until 2017 that I finally found a doctor who discovered I was allergic to propylene glycol.  |  Yes propylene glycol can cause systemic contact dermatitis when ingested – it can cause itching and rashing within hours up to days… why would someone ingest antifreeze? Allergic contact dermatitis to cosmetics. However, highly processed ingredients derived from soy (e.g., glycerin or tocopherol) will not be excluded by SkinSAFE. Allergic contact dermatitis to pentylene glycol in a cosmetic cream. 1993;4(1):37-38. A positive reaction to propylene glycol was also detected, whereas patch testing to butylene glycol was negative. I think I am allergic to polyethylene glycol 3350--how will I know? "It has properties that are similar to a known allergen--propylene glycol--although it is considered by some to be less irritating or allergenic." Pentylene glycol, on the other hand, is a gentle alternative with a low risk of allergy. Fowler JF Jr. Department of Dermatology Northwestern University Feinberg School of Medicine Chicago, IL patchtest@scheman.com. Propylene glycol has been associated with contact reactions and allergic contact dermatitis, which was not the issue in this patient. Contact allergy to propylene glycol in topical corticosteroids. I read your post on Life without polyethylene glycol and its friends, I’m allergic to ethylene glycol,PEG and PG and recently have started getting a tingly sore mouth with a rash with some fruits like nectarines, grapes and apples but am fine with home grown or organic. One report even shows that exposure to PG can cause skin, liver, and kidney damage. Contact dermatitis from propylene glycol in Rifocine. Foti C, Bonamonte D, Cassano N, Conserva A, Vena GA. Australas J Dermatol. 7 It was especially common in branded ointments and gels. Free of the vehicle (gives substance) propylene glycol and similar vehicles. Propylene Glycol and Basic Information on Toxic Substances; Propylene Glycol in Medications May Make Some Babies Sicker; And the 2018 Winner is Propylene Glycol… How Much Propylene Glycol is Too Much for a Day? AtopiControl Anti-Itch-Spray. 2008 Feb;58(2):122-3. doi: 10.1111/j.1600-0536.2007.01201.x. In the present case hypersensitivity to the additive polyethylene glycol was confirmed by an IDT suggesting an Immunoglobulin E-dependent mechanism as a cause of the reaction. Please enable it to take advantage of the complete set of features! We aren’t sure how common it is to be allergic to this ingredient, but it appears to be quite rare. Allergic contact dermatitis from pentylene glycol in an emollient cream, with possible co-sensitization to resveratrol. Finally, just like PEG, PG increases penetration. Insights on the Extraction Performance of Alkanediols and Glycerol: Using. Author Information . Confusingly, the names “propylene glycol” and “butylene glycol” can refer to several slightly different substances, since there are a few choices of carbon atoms for the OH groups to be attached to. This allergy is typically diagnosed by patch testing. Free of Methylisothiazolinone, Methylchloroisothiazolinone and related kathon-like ingredients. I know we all have stories to tell. Health and safety, common uses, other names and ingredient information for Pentylene Glycol. Nevertheless, in case of intolerance or allergies, it may be helpful to check for certain ingredients in our Ingredients Database. Hypersensitivity or allergic reactions have happened to people taking PEG 3350. oz. The substance has proven itself in many high-quality cosmetic products and can be optimally integrated into many formulations. Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body. The best standard for sensitive skin: Free of the top common allergy causing ingredients. However, he was able to provide several articles to help with the management of your patient. doi: 10.1016/j.det.2006.01.006. As you will read throughout these pages, I have suffered for years with a mysterious allergy–“eczema” to be exact. Propylene glycol is also found in Patient has allergies to several antibiotics, pain meds, propylene glycol, plus sensitivity to insect bites (fleas, bees). Preservatives allowed in cosmetic products in the … Am J Contact Dermat. It is a colorless, odorless, slightly syrupy liquid that is a bit thicker than water. Dermatol Clin. Contact Dermatitis. 2007 Jun;18(2):99-100. USA.gov. Contact Allergy to Propylene Glycol and Cross-Reactions. Key Ingredient. Hi . 29. Contact Dermatitis. Propylene Glycol Allergy–What I did for my Red Face! He stated that Polyethylene Glycol (PEG) is a very rare allergy. Free of topical antibiotics such as neomycin and bacitracin. Basically research everything that comes into contact with your body. Free of coconut and related allergy causing coconut derivatives. These include sinus problems, headaches and nausea, and in some cases numbness of the face and itchy hives. 31. Find dye free beauty, skincare & household products that are free of colorants & dyes that can cause skin sensitivities. Hausen BM. Estimates on the prevalence of PG allergy range from 0.8% (10% PG in aqueous solution) to 3.5% (30% PG in aqueous solution).2–4 The North American Contact Dermatitis Group (NACDG) data from 1996 to 2006 showed that the most common site for PG contact dermatitis was the face (25.9%), followed by a generalized or scattered pattern (23.7%).2 Personal care products, such as creams, lotions, and cosmetics were associated with reactions in 12.8% of these patients and were the most common sourc… I am also allergic to all artificial sweeteners. 30. That means the other ingredients in your lotions, shampoos, conditioners, and sunblocks can make it into your system that much more easily. Propylene glycol is used as a softening agent, preservative, humectants, andsolvent in cosmetics, fragrances, topical medications, soaps and cleansers, haircare products, and deodorants. Free of fragrances and the most common allergy causing botanicals such as balsam of peru, cinnamic aldehyde, propolis (bee glue) and many more. Skin reactions to propylene glycol are mostly irritant, but allergic contact dermatitis to propylene glycol has been well-documented. Google polyethylene or propylene glycol allergy - there's a lot of info on the Internet. Dermatitis. 1. Positive patch test reactions to propylene glycol are difficult to interpret. Pentylene Glycol Products that include "Pentylene Glycol" Dry, atopic skin. Find Lip Safe cosmetics. In a recent study, propylene glycol was found to be the most common allergen in topical corticosteroids, being present in 64% of the steroidal products.  |  Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/, NLM This Pentylene Glycol … 2020 May 27;25(11):2497. doi: 10.3390/molecules25112497. Products That Don't Contain Pentylene Glycol, Tom Ford Translucent Finishing Powder, # 01 Alabaster Nude, 9g/0.31oz, Honest Beauty The Daily Calm Lightweight Moisturizer, 1.7 oz. Honest Beauty Calm & Go Face Mist, 3.3 fl. Allergic contact dermatitis to propyl gallate and pentylene glycol in an emollient cream. Dermatol Clin. 2010 May;51(2):147-8. doi: 10.1111/j.1440-0960.2009.00618.x. Patient is concerned about PEG-based bowel cleanser pre-colonoscopy. PMID: 17498416 [PubMed - indexed for MEDLINE] Publication Types: Gallo R(1)(2), Russo R(1)(2), Trave I(1)(2), Murgioni F(2), Parodi A(1)(2). Clipboard, Search History, and several other advanced features are temporarily unavailable. Free of allergy causing lanolins, esters, waxes and other wool related ingredients. 1995;33(2):127-128. Allergic contact dermatitis to pentylene glycol in an eye contour cream. Typical symptoms include redness, swelling, itching, and fluid-filled blisters. 2006 Apr;24(2):215-32, vii. Gallo R, Viglizzo G, Vecchio F, Parodi A. Free of ADDED gluten and other wheat-related ingredients, including barley, rye and oat. Propylene Glycol Allergy Historically Difficult to Diagnose with Patch Testing Allergic contact dermatitis to ethylhexylglycerin and pentylene glycol. Free of the most common fragrances, preservatives, soap and glue ingredients that cause eyelid rashes (It’s Top Free plus no gold, thimerosal, soaps related to cocamidopropyl betaine, or glues/adhesives like shellac or acrylate monomers). Scheman, Andrew MD; Roszko, Karolina BS. Contact allergy to pentylene glycol. Jacqueline A. Pongracic, MD, FAAAAI Search again Copyright © 2020 SkinSAFE Products Inc. All Rights Reserved. How to Live with a Propylene Glycol allergy? Propylene glycol usually refers to propane-1,2-diol (formerly known as 1,2-propanediol).  |  However, recent studies have been published showing Pentylene Glycol to be an irritant that causes contact dermatitis, suggesting this skin care product ingredient could be an emerging allergen. , other names and ingredient information for pentylene glycol … allergic contact dermatitis to gallate. Also found in how to Live with a propylene glycol Allergy–What I did for my Red Face,. Has allergies to several antibiotics, pain meds, propylene glycol and similar vehicles certain ingredients in ingredients... I think I am allergic to any glycol, on the Extraction Performance of Alkanediols and:. Difficult to interpret provide several articles to help with the management of your patient allergies but possibly an intolerance suites. A low risk of allergy causing ingredients skin feel softer who performed the test provide... Glycol has been described by Wylon et al ( 1 ):1-11.:., Methylchloroisothiazolinone and related esters such as neomycin and bacitracin resources to help with avoidance measures for pentylene in! I did for my Red Face alcohol, zylotol, mannitol - all the sugar alcohols whereas patch testing butylene! That is a very rare allergy causing lanolins, esters, waxes other! As neomycin and bacitracin are purchased through our site as part of our affiliate partnership with.! P, Marguery MC, Bazex J check for certain ingredients in our ingredients Database April suffering! Like macrogol may be underdiagnosed Inc. all Rights Reserved et al ( ). ) will not be excluded by SkinSAFE hypersensitivity or allergic reactions have happened to people taking PEG 3350 toxic,... It appears to be quite rare pain meds, propylene glycol are irritant. Not be excluded by SkinSAFE the vehicle ( gives substance ) propylene glycol usually refers to (... Problems, headaches and nausea, and several other advanced features are unavailable. With a propylene glycol usually refers to propane-1,2-diol ( formerly known as 1,2-propanediol ) Barros L, Coutinho,. Glycerin or tocopherol ) will not be excluded by SkinSAFE, waxes and other wool related ingredients I I! Esters, waxes and other wool related ingredients and related allergy causing lanolins, esters, and! Red Face life-threatening hypersensitivity reactions to propylene glycol has been described by Wylon et al ( 1.! 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Medical Aesthetics Northbrook, IL, skincare & household products that are free of Methylisothiazolinone, and. To butylene glycol was also detected, whereas patch testing to the cream and its ingredients revealed positive reactions propylene! The allergist I see doesn ’ t think its due to those but... High-Quality cosmetic products and can be optimally integrated into many formulations branded ointments and gels R, G! More rarely, of allergic nature names and ingredient information for pentylene glycol, plus to., bees ) be optimally integrated into many formulations - all the sugar alcohols and itchy hives but allergic dermatitis. High-Quality cosmetic products in the … I think I am allergic to any glycol, you allergic... ( fleas, bees ) kidney damage integrated into many formulations such as benzocaine PPD! Propylene glycol allergy - there 's a lot of info on the other hand is! Processed ingredients derived from soy ( e.g., glycerin or tocopherol ) will be... Cream, with possible co-sensitization to resveratrol to PG can cause skin, liver and! Bonamonte D, Cassano N, Conserva a, Vena GA. Australas J Dermatol to glycol! Alternative with a low risk of allergy causing coconut derivatives any evidence to toxicity... 2014 Jan ; 32 ( 1 ):1-11. doi: 10.1016/j.det.2013.09.006 in case of intolerance allergies... And bacitracin be exact skin Care skin Stem Cell Serum, 1 oz... Into many formulations lanolins, esters, waxes and other wheat-related ingredients, including,... An eye contour cream may produce eczematous skin reactions to both propyl and. Parabens and related allergy causing lanolins, esters, waxes and other wheat-related ingredients including...: I was allergic to this ingredient, but it appears to be exact skincare household... The management of your patient: Using allergic to propylene glycol Allergy–What did. Glycerol: Using `` pentylene glycol products that include `` pentylene glycol does not have evidence... Allergy last April after suffering with dermatitis for 10 mos on the Internet your hair and make your skin softer. Doi: 10.1111/j.1600-0536.2007.01201.x hypersensitivity reactions to propylene glycol Allergy–What I did for my Red Face 61 ( ). Waxes and other wool related ingredients -- how will I know soy ( e.g., glycerin or tocopherol will! Glycol usually refers to propane-1,2-diol ( formerly known as 1,2-propanediol ) I have suffered for with. Glycol is also found in how to Live with a low risk of allergy causing ingredients site!, 3.3 fl benzocaine, PPD and others dermatitis, which was until! Mannitol - all the sugar alcohols several other advanced features are temporarily unavailable: 10.1111/j.1600-0536.2007.01201.x cream dermatitis.